Thermo Fisher Scientific Gemin 2 Recombinant Rabbit Monoclonal Antibody (ARC2419)
Recombinant rabbit monoclonal antibody against Gemin 2 for WB, IHC, and ELISA. Reacts with human, mouse, and rat samples. High purity (affinity chromatography) and stable liquid form with 0.5 mg/mL concentration. Suitable for research on SMN complex an...
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2419 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human Gemin 2 (UniProt ID: O14893) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897806 |
Product Specific Information
Positive Samples: U2OS, HeLa, MCF7, Mouse testis, Mouse thymus, Rat testis, Rat pancreas
Immunogen Sequence:
MRRAELAGLK TMAWVPAESA VEELMPRLLP VEPCDLTEGF DPSVPPRTPQ EYLRRVQIEA AQCPDVVVAQ IDPKKLKRKQ SVNISLSGCQ PAPEGYSPTL
Target Information
SIP1 is one of the proteins found in the SMN complex, which consists of the survival of motor neuron (SMN) protein and several gemin proteins. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. SIP1 interacts directly with SMN and is required for formation of the SMN complex.
A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. However, knockdown of SIP1 mRNA in motor neurons showed normal motor axons, while knockdown of SMN mRNA resulted in abnormal motor axon outgrowth, indicating that SIP1 may have additional roles outside of the SMN complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific C1 inhibitor Recombinant Rabbit Monoclonal Antibody (ARC2427)
699,900원
Thermo Fisher Scientific
Thermo Fisher Scientific HOXA9 Recombinant Rabbit Monoclonal Antibody (ARC2423)
699,900원
Thermo Fisher Scientific
Thermo Fisher Scientific Gemin 2 Recombinant Rabbit Monoclonal Antibody (ARC2419)
699,900원
Thermo Fisher Scientific
Thermo Fisher Scientific Npr2 Recombinant Rabbit Monoclonal Antibody (ARC2421)
699,900원
Thermo Fisher Scientific
Thermo Fisher Scientific PLA2G2A Recombinant Rabbit Monoclonal Antibody (ARC2416)
699,900원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|