
Thermo Fisher Scientific ACVRL1 Recombinant Rabbit Monoclonal Antibody (024)
인간 ALK-1/ACVRL1 단백질을 인식하는 재조합 토끼 모노클로날 항체로 높은 특이성과 민감도를 제공함. ELISA에 적합하며 보존제가 없는 액상 형태. Protein A로 정제되어 로트 간 일관성이 우수함. 연구용으로만 사용 가능.
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Applications
- ELISA (ELISA)
Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 024 |
| Immunogen | Recombinant Human ALK-1/ACVRL1 protein (Met1–Gln118) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785830 |
Additional Formats
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select the best clones for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the rabbit immune repertoire
This antibody specifically recognizes Human ALK-1/ACVRL1.
Target Information
Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands.
It contains a conserved serine-threonine kinase subdomain, a glycine- and serine-rich GS domain preceding the kinase domain, and a short C-terminal tail.
Mutations in ACVRL1 are associated with:
- Hemorrhagic telangiectasia type 2
- Fibrodysplasia Ossificans Progressiva (FOP)
- Epicanthus
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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