Thermo Fisher Scientific ACVRL1 Recombinant Rabbit Monoclonal Antibody (024)

Applications

• ELISA (ELISA)
  Tested Dilution: 1:5,000–1:10,000

Product Specifications

Additional Formats

• HRP Conjugate
• Request custom conjugation

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select the best clones for production.
Advantages include:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to the rabbit immune repertoire

This antibody specifically recognizes Human ALK-1/ACVRL1.

Target Information

Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands.
It contains a conserved serine-threonine kinase subdomain, a glycine- and serine-rich GS domain preceding the kinase domain, and a short C-terminal tail.
Mutations in ACVRL1 are associated with:

• Hemorrhagic telangiectasia type 2
• Fibrodysplasia Ossificans Progressiva (FOP)
• Epicanthus

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.