
Thermo Fisher Scientific CDKN2C Polyclonal Antibody
CDKN2C 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 검증 완료. 고순도 Protein A 및 항원 친화 크로마토그래피 정제. 인간 및 마우스 반응성. 연구용으로만 사용.
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Thermo Fisher Scientific CDKN2C Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 113–139 amino acids from the C-terminal region of human CDKN2C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2541935 |
Target Information
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. It interacts with CDK4 or CDK6 and prevents activation of CDK kinases, functioning as a cell growth regulator controlling G1 progression.
Ectopic expression suppresses human cell growth correlated with wild-type RB1 function. Knockout mouse studies indicate roles in spermatogenesis and tumorigenesis suppression.
Two alternatively spliced transcript variants encoding an identical protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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