Thermo Fisher Scientific CSNK2A2 Polyclonal Antibody
CSNK2A2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 면역세포화학에 적합하며, 인간과 생쥐 시료에 반응. 1 mg/mL 농도의 액상 제품으로, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CSNK2A2 (Accession P19784), corresponding to amino acid residues A5–F55 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850402 |
Product Specific Information
Antibody detects endogenous levels of total CSNK2A2.
Target Information
Casein kinase II (CK2) is a protein serine/threonine kinase present in all eukaryotic cells, indicating fundamental cellular functions. The holoenzyme is a tetramer containing two alpha or alpha-prime subunits (or one of each) and two beta subunits. The alpha subunit serves as the catalytic unit, while the beta subunit’s function remains unclear.
CK2 can phosphorylate key intracellular signaling proteins involved in tumor suppression (p53, PTEN) and tumorigenesis (myc, jun, NF-kappaB). It also influences Wnt signaling via beta-catenin phosphorylation and the PI3K pathway via Akt phosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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