Thermo Fisher Scientific p27 Kip1 Polyclonal Antibody
Thermo Fisher Scientific의 p27 Kip1 Polyclonal Antibody는 인간 반응성을 가지며, Western blot 및 IHC(Paraffin) 등에 사용됩니다. 세포주기 조절 단백질 p27 Kip1을 타겟으로 하며, 고순도 액상 형태로 안정적 보관이 가능합니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PA518480
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific p27 Kip1 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (KRPATDDSSTQNK) corresponding to internal amino acids of CDKN1B (aa 153–166) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10987100 |
Product Specific Information
This antibody is predicted to react with bovine, canine, feline, mouse, porcine, and rat based on sequence homology.
Tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
p27 Kip1 functions as a negative regulator of G1 phase progression and may mediate TGFβ-induced G1 arrest.
It is a potent inhibitor of cyclin E- and cyclin A-CDK2 complexes and interacts with cyclin D-CDK4 complexes to regulate their activation depending on phosphorylation state.
The protein (~27 kDa) undergoes CDK-dependent phosphorylation and ubiquitination by SCF complexes, enabling the transition from quiescence to proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일은 본문 하단에 위치합니다)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.