Thermo Fisher Scientific SPR Polyclonal Antibody
Thermo Fisher Scientific SPR Polyclonal Antibody는 인간 SPR 단백질을 인식하는 토끼 유래 IgG 항체로, WB, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고순도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications 및 Tested Dilution
| 응용 분야 | 희석 배율 / 농도 |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:5,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SPR. Recombinant protein control fragment (Product #RP-97605) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647886 |
Product Specific Information
Immunogen sequence:
LEEPNVRVLN YAPGPLDTDM QQLARETSVD PDMRKGLQEL KAKGKLVDCK VSAQKLLSLL EKDEFKSGAH VDFY
Highest antigen sequence identity to orthologs:
- Mouse: 74%
- Rat: 73%
Target Information
SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4).
Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency.
A pseudogene has been identified on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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