Thermo Fisher Scientific Crotonyl-HIST1H2BC (Lys23) Polyclonal Antibody
Rabbit polyclonal antibody recognizing Crotonyl-HIST1H2BC (Lys23). Human reactive, validated for ICC/IF and ELISA. Supplied as liquid form in PBS with glycerol, stored at -20°C. For research use only.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:10–1:100
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (17–28aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.16 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Wet ice |
| RRID | AB_2914971 |
Product Specific Information
Antibody tested in Indirect ELISA.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes.
The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher-order structures.
This protein also exhibits antibacterial and antifungal activity. The main transcript variant of this gene is intronless and encodes a replication-dependent histone belonging to the histone H2B family. It lacks a polyA tail but contains a palindromic termination element. The gene is located in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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