Thermo Fisher Scientific Epiregulin Polyclonal Antibody
Epiregulin 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 시료에 반응합니다. ICC/IF 및 ELISA에 사용 가능하며, Protein G로 정제된 5 mg/mL 액상 형태입니다. PBS/glycerol buffer에 보관하며, 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Proepiregulin protein (144–160 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2914975 |
Product Specific Information
Antibody tested in Indirect ELISA.
Target Information
Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not to ErbB2 or ErbB3. It is mainly expressed in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney, and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts, and vascular smooth muscle cells, while inhibiting the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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