Thermo Fisher Scientific NUDT9 Polyclonal Antibody
Human NUDT9 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, 0.4 mg/mL 농도의 액상 형태. PBS/glycerol buffer에 보관하며 연구용으로만 사용 가능.
- 카탈로그번호
- PA560851
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,500–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NUDT9. Recombinant protein control fragment (Product #RP-103725). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644884 |
Product Specific Information
- Immunogen sequence:
PVSGKHILQF VAIKRKDCGE WAIPGGMVDP GEKISATLKR EFGEEALNSL QKTSAEKREI EEKLHKLFSQ DHL - Highest antigen sequence identity to orthologs:
Mouse - 95%, Rat - 95%
Target Information
YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein binds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It binds to promoters containing a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. It regulates transcription of numerous genes and promotes separation of DNA strands that contain mismatches or are modified by cisplatin. It has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), and may play a role in DNA repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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