Thermo Fisher Scientific RRAD Polyclonal Antibody
RRAD 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로 인간 시료에 반응합니다. IHC(P) 및 ICC/IF 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 4°C 또는 -20°C에서 안정적으로 보관 가능합니다.
- 카탈로그번호
- PA559710
- 판매단위
- pk
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Thermo Fisher Scientific RRAD Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RRAD. Recombinant protein control fragment (Product #RP-99865) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646809 |
Product Specific Information
Immunogen sequence:
VGKSALARIF GGVEDGPEAE AAGHTYDRSI VVDGEEASLM VYDIWEQDGG RWLPGHCMAM GDAYVIVYSV TDK
Antigen sequence identity:
- Mouse: 93%
- Rat: 95%
Target Information
The Ras-encoded family of proteins bind GDP and GTP with high affinity and exhibit low intrinsic GTPase activity, which increases significantly upon interaction with cytosolic GTPase activating proteins (GAPs).
Ras family members include H-Ras, K-Ras, N-Ras, M-Ras, R-Ras, ERas, Rheb, TC21, RASL11B, and Rad (Ras associated with diabetes) GTPase.
Rad GTPase is a GTP-binding protein similar to Ras but lacks typical prenylation motifs at its C terminus. It binds calmodulin, inhibits vascular lesion formation, and shows low intrinsic GTPase activity not stimulated by known GAP molecules.
Rad GTPase is expressed in skeletal muscle, cardiac muscle, and lung tissues, and is overexpressed in skeletal muscle of individuals with type II diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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