Thermo Fisher Scientific MRGPRD Polyclonal Antibody
MRGPRD 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC에 적합. 인간 시료 반응성. 합성 펩타이드 면역원 사용. 동결건조 형태로 제공되며, 4°C 또는 -20°C에서 보관 권장. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous (PubMed) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the 4th cytoplasmic loop of human MRGPRD conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: MRGPRD.
Target Information
MRGPRD may regulate nociceptor function and/or development, including the sensation or modulation of pain.
Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evokes Ca(2+) influx in cells expressing the receptor.
Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting coupling with G-protein G(q) and G(i).
Localized at the plasma membrane but internalized into the cytoplasm after beta-alanine treatment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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