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Thermo Fisher Scientific HYPE Polyclonal Antibody, FITC
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Thermo Fisher Scientific HYPE Polyclonal Antibody, FITC

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FITC 형광 표지된 HYPE 폴리클로날 항체로, 인간·마우스·랫트 반응성을 지님. WB, ELISA, IP 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 신뢰성 제공. 연구용으로 ER 스트레스 관련 단백질 분석에 적합.

카탈로그번호
HYPE-FITC
판매단위
pk
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마지막 업데이트 2025. 08. 04. 오전 09:11
Thermo Fisher Scientific HYPE-FITC HYPE Polyclonal Antibody, FITC 200 ul pk판매 단위 pk ·
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543,500원VAT 포함 597,850원

Thermo Fisher Scientific · Thermo Fisher Scientific HYPE Polyclonal Antibody, FITC

Applications

Application Tested Dilution
Western Blot (WB) 1:500–1:5,000
ELISA 1:50,000
Immunoprecipitation (IP) 1:200

Product Specifications

항목 내용
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic peptide corresponding to amino acids within region 400–450 on mouse Protein adenylyltransferase FICD
Conjugate FITC (Fluorescein)
Excitation / Emission Max 498 / 517 nm
Form Liquid
Concentration 0.5–1.5 µg/mL
Purification Antigen affinity chromatography
Storage Buffer Proprietary buffer with 30% glycerol
Contains 0.01% sodium azide
Storage Conditions Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles; store in the dark
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

Protein that can both mediate the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (AMPylation), and the removal of the same modification (de-AMPylation), depending on context.
Acts as a key regulator of the ERN1/IRE1-mediated unfolded protein response (UPR) by mediating AMPylation or de-AMPylation of HSPA5/BiP.
In unstressed cells, AMPylates HSPA5/BiP at Thr-518, inactivating it; under ER stress, de-AMPylates HSPA5/BiP at Thr-518, restoring activity.
Although able to AMPylate RhoA, Rac, and Cdc42 in vitro, these are not physiological substrates.
[UniProt]


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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