Thermo Fisher Scientific CRSP3 Polyclonal Antibody
CRSP3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot 및 Immunoprecipitation에 사용 가능. 인간에 반응하며 Mouse와 Rat에도 예측 반응. 항원 친화 크로마토그래피로 정제된 액상 형태, 4°C 보관.
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Thermo Fisher Scientific CRSP3 Polyclonal Antibody
Applications
- Western Blot (WB): Assay-dependent
- Immunoprecipitation (IP): 1–4 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 1 and 50 of human Cofactor Required for Sp1 transcriptional activation, subunit 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
Target Information
CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex consisting of nine distinct subunits. Several CRSP family members share sequence similarity with yeast transcriptional mediator proteins, including CRSP150 (related to yeast Rgr1) and CRSP70 (similar to elongation factor TFIIS).
CRSP77 and CRSP150 are related to proteins within the putative murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins.
CRSP subunits associate with larger co-activator complexes such as ARC/DRI, which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, and NAT, a polymerase II-interacting complex that represses activated transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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