Thermo Fisher Scientific Epsin 2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 120-300 of human EPN2 (NP_6837232) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Epsin 2,uniProtId:O95208-1,ncbiNodeId:9606,antigenRange:120-300,antigenLength:641,antigenImageFileName:PA5-90935_Epsin_2_O95208-1_Rabbit.svg,antigenImageFileNamePDP:PA5-90935_Epsin_2_O95208-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.48 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806299

Product Specific Information

Immunogen sequence: GINVREKSKQ LVALLKDEER LKAERAQALK TKERMAQVAT GMGSNQITFG RGSSQPNLST SHSEQEYGKA GGSPASYHGS TSPRVSSELE QARPQTSGEE ELQLQLALAM SREVAEQEER LRRGDDLRLQ MALEESRRDT VKIPKKKEHG SLPQQTTLLD LMDALPSSGP AAQKAEPWGP S; Positive Samples: U-87MG, LO2, HeLa; Cellular Location: Cytoplasm, Cytoplasmic vesicle, clathrin-coated vesicle

Target Information

Epsin2 plays a role in the formation of clathrin-coated invaginations and endocytosis. It binds to EPS15 (via the NPF repeat domain), as well as to AP-2 and clathrin (via the DPW repeat domain). The protein resides in the cytoplasm, in punctate structures throughout the cell, associated with clathrin-coated vesicles, and is particularly concentrated in the region of the Golgi complex. Highest expression is found in brain, with lower levels detected in lung and liver.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.