Thermo Fisher Scientific SIRT3 Polyclonal Antibody
SIRT3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot, IHC, ICC/IF에 적합하며 인간 시료에 반응. 항원 친화 크로마토그래피로 정제된 액상 제품으로, 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 338–399 of Human SIRT3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545878 |
Product Specific Information
- Recommended positive control: HepG2
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
SIRT3 is a member of the sirtuin family of proteins, homologous to the yeast Sir2 protein. Members of this family are characterized by a sirtuin core domain and are grouped into four classes. While the functions of human sirtuins are not yet fully determined, yeast sirtuin proteins regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT3 belongs to class I of the sirtuin family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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