Thermo Fisher Scientific FIG4 Polyclonal Antibody
FIG4 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot에 적합하며, 합성 펩타이드(aa 341-390)를 면역원으로 제작되었습니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human FIG4 (aa 341–390) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2691672 |
Target Information
The protein encoded by this gene belongs to the SAC domain-containing protein family.
The SAC domain (~400 amino acids) includes seven conserved motifs with phosphoinositide phosphatase activity.
The yeast homolog Sac1p regulates phosphoinositides and influences actin cytoskeleton organization, Golgi function, and vacuole morphology.
Membrane-bound phosphoinositides act as signaling molecules and are crucial for vesicle trafficking in eukaryotic cells.
Mutations in this gene are associated with Charcot-Marie-Tooth disease type 4J.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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