Thermo Fisher Scientific ANKRD13A Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human AN13A. Recombinant protein control fragment (Product #RP-97637). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ANKRD13A,uniProtId:Q8IZ07-1,ncbiNodeId:9606,antigenRange:425-492,antigenLength:590,antigenImageFileName:PA5-58812_ANKRD13A_Q8IZ07-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58812_ANKRD13A_Q8IZ07-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637925

Product Specific Information

Immunogen sequence: FGNVNGCSTA EESVSQNVEG TQADSASHIT NFEVDQSVFE IPESYYVQDN GRNVHLQDED YEIMQFAI

Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 86%.

Target Information

ANKRD13A, also named as ANKRD13, a 590 amino acid protein, which contains two ANK repeats and four UIM (ubiquitin-interacting motif) repeats. ANKRD13A localizes in the cell membrane. ANKRD13A as ubiquitin-binding protein that specifically recognizes and binds Lys-63-linked ubiquitin, not bind Lys-48-linked ubiquitin. ANKRD13A positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.