Thermo Fisher Scientific ANKRD13A Polyclonal Antibody
Human ANKRD13A 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC 및 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 4°C 단기, -20°C 장기 보관 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000–1:2,500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human AN13A. Recombinant protein control fragment (Product #RP-97637). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637925 |
Product Specific Information
Immunogen sequence:
FGNVNGCSTA EESVSQNVEG TQADSASHIT NFEVDQSVFE IPESYYVQDN GRNVHLQDED YEIMQFAI
Ortholog Identity:
- Mouse: 82%
- Rat: 86%
Target Information
ANKRD13A (also named ANKRD13) is a 590 amino acid protein containing two ANK repeats and four UIM (ubiquitin-interacting motif) repeats.
It localizes to the cell membrane and acts as a ubiquitin-binding protein that specifically recognizes and binds Lys-63-linked ubiquitin, but not Lys-48-linked ubiquitin.
ANKRD13A positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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