Thermo Fisher Scientific TBC1D22A Polyclonal Antibody
Human TBC1D22A 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:25–1:100 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein of human TBC1 domain family, member 22A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636253 |
Product Specific Information
This antibody detects endogenous levels of total TBC1D22A protein.
Target Information
TBC1D22A (TBC1 domain family, member 22A), also known as C22orf4, is a 517 amino acid protein containing one Rab-GAP TBC domain. It is believed to function as a GTPase-activating protein for Rab family members. Multiple isoforms exist due to alternative splicing.
The gene encoding TBC1D22A is located on human chromosome 22, which contains over 500 genes and is the second smallest human chromosome. Mutations in genes on chromosome 22 are associated with conditions such as Phelan-McDermid syndrome, neurofibromatosis type 2, autism, and schizophrenia.
Translocations between chromosomes 9 and 22 can result in the Philadelphia chromosome, producing the BCR-Abl fusion protein—a potent activator of cell proliferation found in several types of leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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