Thermo Fisher Scientific FAM193B Polyclonal Antibody
Human FAM193B 단백질을 타겟으로 하는 Rabbit Polyclonal Antibody로, ICC/IF 실험에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태이며, PBS 기반 버퍼에 40% 글리세롤 포함. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FAM193B (UniProt ID: Q96PV7-1, Range: 668–753) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791517 |
Product Specific Information
Immunogen sequence:
NTVPNLSRVI WVKTPKPGYP SSEEPSSKEV PSCKQELPEP VSSGGKPQKG KRQGSQAKKS EASPAPRPPA SLEVPSAKGQ VAGPKQ
Target Information
FAM193B, also known as IRIZIO, was initially identified as a protein upregulated in alveolar rhabdomyosarcoma (ARMS), a fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with FOXO1. In PAX3-FOXO1-expressing primary mouse fibroblasts with a defective p53 pathway, FAM193B expression enabled tumorigenic transformation, suggesting its contribution to rhabdomyosarcomagenesis in humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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