Thermo Fisher Scientific SQSTM1 Monoclonal Antibody (OTI7F6), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The SQSTM1 gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-κB) signaling pathway.
This protein acts as a scaffolding/adaptor molecule with TNF receptor-associated factor 6 (TRAF6) to mediate NF-κB activation in response to upstream signals.
Alternative splicing results in multiple transcript variants.
Mutations in this gene are associated with sporadic and familial Paget disease of bone.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.