Thermo Fisher Scientific MYOZ1 Monoclonal Antibody (OTI2A2), TrueMAB
MYOZ1 단백질을 인식하는 단클론 항체로, Western blot에 최적화됨. Human, Mouse, Rat 반응성. 동결건조 형태로 제공되며, PBS buffer와 trehalose 포함. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 106–299 of human MYOZ1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Sarcomere assembly is regulated by the muscle protein titin, a giant elastic protein with kinase activity. Titin acts as a scaffold for myofibrils and muscle-related proteins.
The MYOZ1 gene encodes a protein found in striated and cardiac muscle that binds to titin Z1–Z2 domains and serves as a substrate for titin kinase—interactions critical for sarcomere assembly.
Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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