Thermo Fisher Scientific BCAS1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human BCAS1 protein. Validated for Western blot and IHC applications. Lyophilized form without preservative, reconstitute in sterile water. Suitable for research use in cancer and cell proliferation studies.
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- OSB00087W-100UL
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
- Publications: References available
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
- Publications: References available
Miscellaneous PubMed (Misc)
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 500–550 of human BCAS1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: BCAS1.
Target Information
BCAS1 was identified through positional cloning and found to be overexpressed in most breast cancer cell lines. BCAS1 is cytoplasmically localized and forms homodimers through coiled-coil structures. High BCAS1 mRNA levels are observed in brain and prostate tissues, with lower levels in colon, intestine, and testis. Overexpression does not alter anchorage-dependent growth or proliferation rate, suggesting BCAS1 is not a typical oncogene. It is also amplified in pancreatic carcinoma, indicating a potential role in cell proliferation control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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