Thermo Fisher Scientific CD299 (DC-SIGN/L) Polyclonal Antibody
CD299 (DC-SIGN/L) 폴리클로날 항체로 인간 CLEC4M 단백질을 인식합니다. IHC(P) 실험에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 4°C 또는 -20°C에서 안정적으로 보관 가능합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CLEC4M. Recombinant protein control fragment (Product #RP-98388). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639880 |
Product Specific Information
- Immunogen sequence: GLLEEDPTTS GIRLFPRDFQ FQQIHGHKSS TGCLGH
- Highest antigen sequence identity to orthologs: Mouse – 36%, Rat – 36%.
Target Information
CLEC4M is a type II integral membrane protein that is 77% identical to CD209 antigen (HIV gp120-binding protein). Like CD209, it binds ICAM3 and HIV-1 gp120, enhancing HIV-1 infection of T cells.
Western blots using two different antibodies against unique regions of this protein confirm consistent molecular weight.
This gene is mapped to 19p13.3, clustered with CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants exist, though some biological validity remains unclear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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