Thermo Fisher Scientific Phospho-GSK3 alpha (Ser21) Polyclonal Antibody
GSK3 alpha의 Ser21 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, IP에 적합. Human, Mouse, Rat 시료 반응성. 1 mg/mL 농도의 액상 형태로, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GSK3A (Accession P49840), corresponding to amino acid residues around phosphorylated Ser21. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818309 |
Product Specific Information
This antibody detects endogenous levels of GSK3 alpha only when phosphorylated at Serine 21.
Target Information
Glycogen synthase kinase 3 alpha (GSK3A) is a multifunctional protein serine/threonine kinase implicated in the regulation of several proteins and transcription factors.
(GSK3A Alias: DKFZp686D0638)
Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2, which share 55% amino acid sequence identity and have been implicated in human carcinogenesis. The GSTT1 gene is located approximately 50 kb from the GSTT2 gene, and both share a similar structure composed of five exons with identical exon/intron boundaries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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