Thermo Fisher Scientific RPRD1B Polyclonal Antibody
RPRD1B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, 액상 형태로 제공됩니다. 1 mg/mL 농도, 4°C 보관, 연구용 전용 제품입니다.
- 카탈로그번호
- A303782Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RPRD1B Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 276 and 326 of Human Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B, UniProt ID: Q9NQG5-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit (POLR2A) and participates in CTD dephosphorylation by RPAP2.
Acts as a transcriptional regulator enhancing expression of CCND1 and other cell cycle-related genes such as CDK2, CDK4, CDK6, and cyclin-E, but not CDKN1A, CDKN1B, or cyclin-A.
Promotes RNA polymerase II binding to promoter and termination regions, prevents read-through beyond the 3′ termination site, and may facilitate chromatin loop formation for transcription re-initiation.
Promotes cell proliferation. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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