Thermo Fisher Scientific SMC1A Monoclonal Antibody (OTI2D12), TrueMAB
SMC1A 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 IHC(P) 적용 가능. 인간 및 생쥐 반응성. 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol 버퍼 포함. 염색체 구조 유지 관련 연구용에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 889–1016 of human SMC1A produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair, and global transcriptional repression. These proteins are conserved in eukaryotes and are essential for proper mitotic chromosome segregation. The SMC1 and SMC3 form a heterodimeric complex required for metaphase progression and sister chromatid cohesion. Mutations in the SMC1A gene can lead to Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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