Thermo Fisher Scientific RGS13 Monoclonal Antibody (OTI4G1), TrueMAB
인간 RGS13 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 최적화되어 있습니다. 비결합형 액상 형태이며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능하며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G1 |
| Immunogen | Full length human recombinant protein of human RGS13 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
RGS13 is the smallest member of the mammalian RGS (Regulators of G protein-signaling) family, homologous to yeast SST2 and C. elegans egl-10 proteins. RGS proteins act as GTPase-activating proteins (GAPs) for Ga subunits, attenuating G protein-mediated signaling.
RGS13 is highly expressed in human tonsil, thymus, lung, lymph node, and spleen. It regulates Gai, Gaq, and Gas coupled signaling cascades and serves as a GTPase-activating protein for Gai and Gao.
This protein blocks MAPK activity induced by Gai- or Gaq-coupled receptors and attenuates GTPase-deficient Gaq (GaqQL) mediated cAMP response element activation.
The human RGS13 gene is localized on chromosome 1q31.2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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