Thermo Fisher Scientific CD335 (NKp46) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 151-303 of human NCR1 (NP_0011389292) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NKp46 (CD335),uniProtId:O76036-1,ncbiNodeId:9606,antigenRange:151-303,antigenLength:304,antigenImageFileName:PA5-89869_NKp46_CD335_O76036-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89869_NKp46_CD335_O76036-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.41 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805812

Product Specific Information

Immunogen sequence: SMFLLLKEGR SSHVQRGYGK VQAEFPLGPV TTAHRGTYRC FGSYNNHAWS FPSEPVKLLV TGDIENTSLA PEDPTFPDTW GTYLLTTETG LQKDHALWDH TAQNLLRMGL AFLVLVALVW FLVEDWLSRK RTRERASRAS TWEGRRRLNT QTL; Positive Samples: A-549, Mouse spleen, Mouse thymus, Rat spleen, Rat lung; Cellular Location: Cell membrane, Single-pass type I membrane protein

Target Information

NKp46 (CD335, NCR1, ) is a cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. NKp46 consists of two Ig-like domains assembled to leukocyte immunoglobulin-like (LIR) and killer inhibitory receptors (KIR).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.