Thermo Fisher Scientific DLL3 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA2046)

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Cynomolgus monkey, Human

Host/Isotype

Alpaca / VHH

Expression System

CHO cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

SAA2046

Immunogen

Recombinant Human DLL3.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.22 mg/mL

Purification

Metal-chelate chromatography

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Product Specific Information

Compatible with Direct ELISA

Target Information

Delta-like protein 3 (DLL3) is a ligand for the Notch signaling pathway. It inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in DLL3 gene cause truncal shortening relative to their limbs, which leads to abdominal protrusion, abnormal spinal curvature and sometimes a plagiocephaly-torticollis sequence. It may be required to divert neurons along a specific differentiation pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.