Thermo Fisher Scientific DLL3 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA2046)
DLL3 단백질을 표적으로 하는 알파카 유래 재조합 단일클론 항체입니다. Flow Cytometry와 ELISA에서 사용 가능하며, CHO 세포에서 발현되었습니다. 금속 킬레이트 크로마토그래피로 정제되었고, PBS 용액 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cynomolgus monkey, Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA2046 |
| Immunogen | Recombinant Human DLL3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.22 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Delta-like protein 3 (DLL3) is a ligand for the Notch signaling pathway and inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.
Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in the DLL3 gene can lead to truncal shortening relative to limbs, abdominal protrusion, abnormal spinal curvature, and sometimes a plagiocephaly-torticollis sequence. It may be required to divert neurons along a specific differentiation pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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