Thermo Fisher Scientific CCRL2 Polyclonal Antibody
Human CCRL2 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 8 µg/mL로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS에 0.1% sodium azide 포함. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 8 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human CCRL2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550791 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon (100%)
- Monkey (95%)
- Marmoset (90%)
Target Information
CCRL2 (C-C chemokine receptor-like 2), also known as chemokine receptor X, human chemokine receptor (HCR), CRAM-A or CRAM-B, is a seven-pass transmembrane protein expressed by monocytes, neutrophils, and dendritic cells of immune tissues (predominantly spleen, fetal liver, bone marrow, and lymph node).
It shares over 40% homology with other C-C chemokine receptors but lacks the conserved DRY motif necessary for signaling and ligand-binding.
C-C chemokine receptors are G-protein coupled, seven-pass transmembrane domain proteins whose main physiological role is to mediate chemotaxis of T cells and phagocytic cells to sites of inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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