Thermo Fisher Scientific CCRL2 Polyclonal Antibody

Applications and Tested Dilution

• Immunohistochemistry (Paraffin) (IHC (P)): 8 µg/mL

Product Specifications

Product Specific Information

Percent identity with other species by BLAST analysis:

• Human, Gorilla, Gibbon (100%)
• Monkey (95%)
• Marmoset (90%)

Target Information

CCRL2 (C-C chemokine receptor-like 2), also known as chemokine receptor X, human chemokine receptor (HCR), CRAM-A or CRAM-B, is a seven-pass transmembrane protein expressed by monocytes, neutrophils, and dendritic cells of immune tissues (predominantly spleen, fetal liver, bone marrow, and lymph node).
It shares over 40% homology with other C-C chemokine receptors but lacks the conserved DRY motif necessary for signaling and ligand-binding.
C-C chemokine receptors are G-protein coupled, seven-pass transmembrane domain proteins whose main physiological role is to mediate chemotaxis of T cells and phagocytic cells to sites of inflammation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.