Thermo Fisher Scientific UBE3C Polyclonal Antibody
Thermo Fisher Scientific의 UBE3C Polyclonal Antibody는 Human 및 Mouse 시료에 반응하며, Western blot과 Immunocytochemistry에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 항체로, 1 mg/mL 농도이며 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 114–387 of Human UBE3C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2548824 |
Product Specific Information
- Recommended positive controls: HeLa, HepG2, HCT116, mouse brain
- Predicted reactivity: Mouse (88%), Chicken (87%), Bovine (89%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
Can assemble unanchored poly-ubiquitin chains in either Lys-29- or Lys-48-linked polyubiquitin chains, with preference for Lys-48 linkages.
It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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