Thermo Fisher Scientific CBLL1 Polyclonal Antibody
Human CBLL1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼에 40% 글리세롤과 0.02% 나트륨 아지드가 포함되어 있습니다. 연구용으로만 사용됩니다.
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- PA554503
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | View publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CBLL1. Recombinant protein control fragment (Product #RP-92641) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639326 |
Product Specific Information
Immunogen sequence:
RKHSNLITVP IQDDSNSGAR EPPPPAPAPA HHHPEYQGQP VVSHPHHIMP PQQHYAPPPP PPPPISHPMP
Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 99%
Target Information
This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation.
A related pseudogene has been identified on chromosome X.
Alternative splicing results in a non-coding transcript variant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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