Thermo Fisher Scientific SOD3 Polyclonal Antibody
SOD3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 IHC(파라핀 절편)에 적합하며, 인간, 마우스, 랫트 시료에 반응. 친화 크로마토그래피로 정제된 액상 항체로, -20°C 보관.
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human SOD3 (amino acids 128–149) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691783 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. It is widely expressed in human tissues and shows increased expression in actively dividing cells such as those in testis, thymus, fetal liver, and carcinomas. The encoded protein localizes to the nucleus and promotes the stability and nuclear accumulation of transcriptionally active p53. It phosphorylates Thr18 of p53, reducing its ubiquitination and potentially regulating cell proliferation. Additionally, this protein phosphorylates histone, casein, and transcription factors ATF2 and c-JUN.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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