Thermo Fisher Scientific PRDM12 Polyclonal Antibody
PRDM12 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간 및 생쥐 시료에 반응. Western blot과 ELISA에 적합하며, 고순도 Affinity Chromatography로 정제된 액상 형태. 통증 인식 관련 유전자 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 100–330 of human PRDM12 (NP_067632.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.95 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855626 |
Product Specific Information
Immunogen sequence:
LGIFSKTWIK AGTEMGPFTG RVIAPEHVDI CKNNNLMWEV FNEDGTVRYF IDASQEDHRS WMTYIKCARN EQEQNLEVVQ IGTSIFYKAI EMIPPDQELL VWYGNSHNTF LGIPGVPGLE EDQKKNKHED FHPADSAAGP AGRMRCVICH RGFNSRSNLR SHMRIHTLDK PFVCRFCNRR FSQSSTLRNH VRLHTGERPY KCQVCQSAYS QLAGLRAHQK SARHRPPSTA L
Target Information
This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception.
The encoded protein contains:
- N-terminal PRDI-BF1 and RIZ homology (PR) domain
- SET domain
- Three C-terminal C2H2 zinc finger DNA-binding domains
Naturally occurring mutations in this gene are associated with:
- Congenital insensitivity to pain (CIP)
- Hereditary sensory and autonomic neuropathies (HSANs)
Deregulation of this gene is linked to solid cancers and hematological malignancies including chronic myeloid leukemia.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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