Thermo Fisher Scientific PRDM12 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

ELISA

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:

LGIFSKTWIK AGTEMGPFTG RVIAPEHVDI CKNNNLMWEV FNEDGTVRYF IDASQEDHRS WMTYIKCARN EQEQNLEVVQ IGTSIFYKAI EMIPPDQELL VWYGNSHNTF LGIPGVPGLE EDQKKNKHED FHPADSAAGP AGRMRCVICH RGFNSRSNLR SHMRIHTLDK PFVCRFCNRR FSQSSTLRNH VRLHTGERPY KCQVCQSAYS QLAGLRAHQK SARHRPPSTA L

Target Information

This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception.
The encoded protein contains:

• N-terminal PRDI-BF1 and RIZ homology (PR) domain
• SET domain
• Three C-terminal C2H2 zinc finger DNA-binding domains

Naturally occurring mutations in this gene are associated with:

• Congenital insensitivity to pain (CIP)
• Hereditary sensory and autonomic neuropathies (HSANs)

Deregulation of this gene is linked to solid cancers and hematological malignancies including chronic myeloid leukemia.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지