Thermo Fisher Scientific VASH1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human VASH1. Recombinant protein control fragment (Product #RP-88864). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:VASH1,uniProtId:Q7L8A9-1,ncbiNodeId:9606,antigenRange:216-357,antigenLength:365,antigenImageFileName:PA5-51434_VASH1_Q7L8A9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51434_VASH1_Q7L8A9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649394

Product Specific Information

Immunogen sequence: GALGMSRRED LMYKPPAFRT LSELVLDFEA AYGRCWHVLK KVKLGQSVSH DPHSVEQIEW KHSVLDVERL GRDDFRKELE RHARDMRLKI GKGTGPPSPT KDRKKDVSSP QRAQSSPHRR NSRSERRPSG DKKTSEPKAM PD

Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

Target Information

VASH1 is a protein that possesses actin binding activity and metallocarboxypeptidase activity. It is involved in several processes including negative regulation of angiogenesis, negative regulation of blood vessel endothelial cell migration, and proteolysis. VASH1 acts upstream of or within processes such as negative regulation of endothelial cell migration, negative regulation of endothelial cell proliferation, and negative regulation of lymphangiogenesis. It is located in the apical part of the cell, endoplasmic reticulum, and extracellular space. VASH1 is implicated in liver cirrhosis and portal hypertension, and is a biomarker of liver cirrhosis. Diseases associated with VASH1 include Portal Hypertension and Myasthenic Syndrome, Congenital, 14.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.