Thermo Fisher Scientific VASH1 Polyclonal Antibody
Human VASH1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 응용에 적합하며, 높은 특이성과 재현성을 제공. 항원 친화 크로마토그래피로 정제된 액상 형태로, 연구용으로 사용 가능.
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Applications
- Western Blot (WB): 0.04–0.4 µg/mL
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human VASH1. Recombinant protein control fragment (Product #RP-88864). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649394 |
Product Specific Information
Immunogen sequence:
GALGMSRRED LMYKPPAFRT LSELVLDFEA AYGRCWHVLK KVKLGQSVSH DPHSVEQIEW KHSVLDVERL GRDDFRKELE RHARDMRLKI GKGTGPPSPT KDRKKDVSSP QRAQSSPHRR NSRSERRPSG DKKTSEPKAM PD
Highest antigen sequence identity to orthologs:
- Mouse: 96%
- Rat: 96%
Target Information
VASH1 is a protein with actin binding and metallocarboxypeptidase activity. It plays roles in:
- Negative regulation of angiogenesis
- Inhibition of endothelial cell migration and proliferation
- Regulation of lymphangiogenesis
Localization: Apical part of the cell, endoplasmic reticulum, extracellular space.
Associated diseases: Liver cirrhosis, portal hypertension, congenital myasthenic syndrome (type 14).
Biomarker: Liver cirrhosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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