Thermo Fisher Scientific SSB Polyclonal Antibody
SSB 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응합니다. Western blot, IHC, ICC/IF, IP 등 다양한 응용에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 장기 보관 시 -20°C에서 보관을 권장합니다.
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Thermo Fisher Scientific SSB Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | View 1 publication |
| Immunoprecipitation (IP) | - | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 6–242 of Human SSB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.52 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547237 |
Product Specific Information
- Recommended positive controls: 293T, JC, C2C12
- Predicted reactivity: Mouse (89%), Rat (89%), Chimpanzee (99%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
La protein is involved in various aspects of RNA metabolism, including:
- Binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA
- Processing 5-prime and 3-prime ends of pre-tRNA precursors
- Acting as an RNA chaperone
- Binding viral RNAs associated with hepatitis C virus
La protein was originally defined by its reactivity with autoantibodies from patients with Sjögren syndrome and systemic lupus erythematosus.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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