Thermo Fisher Scientific SIAH1 Polyclonal Antibody
SIAH1 단백질을 인식하는 Goat polyclonal antibody로, 인간 및 랫트 반응성. Western blot과 Immunocytochemistry에 적합. 0.5 mg/mL 농도의 액상 형태로 제공되며, TBS buffer(pH 7.3, 0.5% BSA) 포함. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (SRQTATALPTGTSKC) corresponding to the N-terminus amino acids of SIAH1 (aa 2–16) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10985773 |
Product Specific Information
- Recognizes both reported isoforms (NP_003022.3; NP_001006611.1).
- Predicted to react with bovine and canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 128,000.
Target Information
This gene encodes a protein that is a member of the seven in absentia homolog family. The protein acts as an E3 ligase involved in ubiquitination and proteasome-mediated degradation of specific proteins. Its activity is implicated in:
- Development of certain forms of Parkinson’s disease
- Regulation of cellular response to hypoxia
- Induction of apoptosis
Alternative splicing results in several transcript variants, encoding different isoforms or uncharacterized forms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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