Thermo Fisher Scientific Chemerin Monoclonal Antibody (D2)
Rat Chemerin 단백질을 인식하는 D2 클론의 Mouse Monoclonal Antibody. Western blot에 최적화된 고순도 단백질 A/G 정제 항체. PBS/glycerol buffer에 보존되어 안정적이며 연구용으로만 사용 가능.
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Thermo Fisher Scientific Chemerin Monoclonal Antibody (D2)
Applications
- Western Blot (WB): 0.01–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | D2 |
| Immunogen | Recombinant Rat CHEM protein, Ser25–Gly152 (Accession #Q5BK77) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090358 |
Target Information
Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs). Tazarotene-induced gene (TIG) proteins, also designated retinoic acid receptor responder proteins or RAR-responsive proteins, can be membrane bound or secreted. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. TIG2 is a secreted protein that is mainly expressed in epidermis, hair follicles and endothelial cells. TIG2 is inhibited in psoriatic lesions and is activated by tazarotene in skin rafts and in epidermis of psoriatic lesions.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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