Thermo Fisher Scientific c-Ros Polyclonal Antibody
Thermo Fisher Scientific의 c-Ros Polyclonal Antibody는 Human, Mouse, Rat에 반응하는 Rabbit IgG 폴리클로날 항체입니다. Western Blot, IHC, Flow Cytometry, ELISA 등에 사용 가능하며, Protein A로 정제된 1 mg/mL 액상 형태입니다. 연구용으로 -20°C에 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human c-Ros (amino acids 2231–2347) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ROS1 is a tyrosine kinase that functions as a growth or differentiation factor receptor. Protein kinases transfer phosphate groups from ATP to substrate proteins, mediating signal transduction in eukaryotic cells. They regulate metabolism, transcription, cell cycle, cytoskeletal rearrangement, movement, apoptosis, and differentiation.
The protein kinase family includes over 500 gene products, classified into 8 major groups based on catalytic domain sequences. Tyrosine kinases (TK) regulate cell-cell interactions such as differentiation, adhesion, motility, and death. Approximately 90 TK genes have been sequenced, including 58 receptor TKs (EGFR, EPH, FGFR, PDGFR, TRK, VEGFR) and 32 cytosolic TKs (ABL, FAK, JAK, SRC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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