Thermo Fisher Scientific PLAC1 Polyclonal Antibody
인간 PLAC1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 ICC/IF에 적합합니다. 액상 형태로 제공되며 항원 친화 크로마토그래피로 정제되었습니다. 인체 태반 및 암세포 연구에 활용 가능하며, 연구용으로만 사용됩니다.
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Thermo Fisher Scientific PLAC1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the carboxy terminus of human PLAC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153254 |
Product Specific Information
- Suggested positive control: human placenta lysate
- PA5-21044 can be used with blocking peptide PEP-1158.
Target Information
PLAC1 was initially identified as a protein expressed specifically in the placenta and other trophoblast-derived cells during embryonic development. It is also ectopically expressed in various human malignancies, particularly breast cancers.
PLAC1 is a membrane-associated protein thought to serve a receptor-like function, modulating cell-cell or ligand-receptor interactions at the maternal-placental interface.
Decreased PLAC1 expression correlates with reduced cyclin D1 and AKT kinase levels, suggesting PLAC1 may be a promising candidate for cancer immunotherapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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