Thermo Fisher Scientific Phospho-GluR1 (Thr840) Polyclonal Antibody
Rabbit 유래의 폴리클로날 항체로, GluR1 (Thr840) 인산화 부위를 특이적으로 인식. Western blot, IHC, ICC, IP에 적합. 인간 단백질과의 교차 반응 예측. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Immunoprecipitation (IP) | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 850 to the C-terminus of Mouse Glutamate Receptor 1 (AMPA subtype), phosphorylated at pThr840 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10982349 |
Product Specific Information
This antibody is predicted to react with human based on sequence homology.
Target Information
GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of L-glutamate induces a conformational change that opens the cation channel, converting the chemical signal into an electrical impulse. The receptor then rapidly desensitizes into a transient inactive state characterized by a bound agonist. In the presence of CACNG4, CACNG7, or CACNG8, GluR1 exhibits resensitization, marked by delayed current flux accumulation upon continued glutamate application.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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