Thermo Fisher Scientific ESX1 Polyclonal Antibody
인간 ESX1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체. 높은 특이성과 재현성을 제공하며, 연구용으로 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ESX1 Polyclonal Antibody
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,500–1:5,000
Immunocytochemistry (ICC/IF)
- Tested Concentration: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ESX1. Recombinant protein control fragment (Product #RP-100051) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641131 |
Product Specific Information
Immunogen sequence:
HEPEQQQEEP PLLELKQEQE EPPQTTVEGP QPAEGPQTAE GPQPPERKRR RRTAFTQFQ
Antigen sequence identity:
- Mouse: 37%
- Rat: 36%
Target Information
Homeobox proteins are transcription factors containing a helix-turn-helix DNA binding domain called the homeodomain.
ESX1 is an X-linked homeobox gene primarily expressed in the placenta and testis, with two functional domains: the homeodomain and a proline-rich domain.
During embryogenesis, ESX1 is expressed in extraembryonic tissues, including the endoderm of the visceral yolk sac, ectoderm of the chorion, and labyrinthine trophoblast of the chorioallantoic placenta.
ESX1 can act as a transcriptional repressor to the human oncogene K-ras. Treatment of human cancer cells with an ESX1 protein fragment containing the homeodomain reduces tumorigenicity in cells with oncogenic K-ras mutations, suggesting potential therapeutic relevance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.