Thermo Fisher Scientific alpha E-Catenin/alpha N-Catenin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human CTNNA1/CTNNA2, corresponding to a region within C-terminal amino acids. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:alpha E-Catenin/alpha N-Catenin,uniProtId:P26232-1,ncbiNodeId:9606,antigenRange:953,antigenLength:953,antigenImageFileName:PA5-99602_alpha_E-Cateninalpha_N-Catenin_P26232-1_Rabbit.svg,antigenImageFileNamePDP:PA5-99602_alpha_E-Cateninalpha_N-Catenin_P26232-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:alpha E-Catenin/alpha N-Catenin,uniProtId:P35221-1,ncbiNodeId:9606,antigenRange:906,antigenLength:906,antigenImageFileName:PA5-99602_alpha_E-Cateninalpha_N-Catenin_P35221-1_Rabbit.svg,antigenImageFileNamePDP:PA5-99602_alpha_E-Cateninalpha_N-Catenin_P35221-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2818535

Product Specific Information

Antibody detects endogenous levels of total CTNNA1/CTNNA2.

Target Information

This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.