Thermo Fisher Scientific Nicotinic Acetylcholine Receptor alpha 7 Polyclonal Antibody, Biotin
Biotin으로 표지된 다클론성 항체로, Nicotinic Acetylcholine Receptor alpha 7을 검출. WB, ELISA, IP 등 다양한 응용에 적합. Mouse 및 Rat 반응성. 고순도 Affinity chromatography 정제 및 안정적인 액상 형태 제공.
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- NACR-BIOTIN
- 판매단위
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 25–75 on mouse GTPCHI protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) containing 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Chromosome 15 encodes over 700 genes and comprises nearly 3% of the human genome.
CHRFAM7A, a fusion protein comprised of FAM7A and AChR alpha7, is encoded by the CHRFAM7A gene, located on a region of human chromosome 15 associated with neuropsychiatric disorders such as schizophrenia and bipolar affective disorder.
CHRFAM7A (also known as D-10 or CHRNA7) is a 412 amino acid multi-pass membrane protein belonging to the nicotinic acetylcholine receptor (nAChR) subfamily of ligand-gated ion channel proteins, mediating synaptic signal transmission.
CHRFAM7A is expressed in the hippocampus, and alternative splicing produces two splice variants.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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