Thermo Fisher Scientific RGS4 Polyclonal Antibody
RGS4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, Human, Mouse, Rat 등 다양한 종에 반응. 액상 형태로 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RGS4 (Accession P49798), corresponding to amino acid residues K162–A205 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853424 |
Product Specific Information
Antibody detects endogenous levels of total RGS4.
Target Information
Regulator of G protein signaling (RGS) family members act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins.
RGS proteins deactivate G protein subunits of the Gi alpha, Go alpha, and Gq alpha subtypes, driving them into their inactive GDP-bound forms.
RGS4 belongs to this family and shares a conserved 120-amino acid RGS domain.
RGS4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4.
It negatively regulates signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.
Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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