
Thermo Fisher Scientific B4GALT5 Monoclonal Antibody (6D8)
B4GALT5 단백질을 인식하는 Mouse monoclonal antibody (Clone 6D8). Western blot 및 ELISA에 적합하며, Human 시료 반응성. 액상 형태로 제공, 보존제 없음. -20°C 보관 권장.
- 카탈로그번호
- H00009334-M07A
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: References
ELISA
- Tested Dilution: 1:500–1:1,000
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6D8 |
| Immunogen | B4GALT5 (NP_004767, 48–151 a.a) partial recombinant protein with GST tag. MW of GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
AQGILIRDNV RTIGAQVYEQ VLRSAYAKRN SSVNDSDYPL DLNHSETFLQ TTTFLPEDFT YFANHTCPER LPSMKGPIDI NMSEIGMDYI HELFSKDPTI KLGG
Target Information
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that have specificity for the donor substrate UDP-galactose and transfer galactose in a β1,4 linkage to acceptor sugars such as GlcNAc, Glc, and Xyl.
Each beta4GalT has distinct functions in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and remains uncleaved to function as a transmembrane anchor.
By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7.
The enzyme encoded by this gene was previously designated as B4GALT4 but renamed to B4GALT5. It is also referred to as beta4GalT2 in literature.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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