Thermo Fisher Scientific GTF3C3 Monoclonal Antibody (3D9)
상품 옵션 정보 | ||||||||
---|---|---|---|---|---|---|---|---|
카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
H00009330-M02 | - | Thermo Fisher Scientific H00009330-M02 GTF3C3 Monoclonal Antibody (3D9) 100 ug pk | 재고문의 | pk | 520,000원 | - | 572,000원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1-5 µg/mL
ELISA (ELISA)
10 µg/mL
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse / IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
3D9
Immunogen
GTF3C3 (NP_036218, 112 a.a. approximately 214 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
GTF3C3,
uniProtId:
Q9Y5Q9-1,
ncbiNodeId:
9606,
antigenRange:
112-214,
antigenLength:
886,
antigenImageFileName:
H00009330-M02_GTF3C3_Q9Y5Q9-1_House_mouse.svg,
antigenImageFileNamePDP:
H00009330-M02_GTF3C3_Q9Y5Q9-1_House_mouse_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: TPEQPTAGDV FVLEMVLNRE TKKMMKEKRP RSKLPRALRG LMGEANIRFA RGEREEAILM CMEIIRQAPL AYEPFSTLAM IYEDQGDMEK SLQFELIAAH LNP
Target Information
RNA polymerase (pol) III synthesizes tRNA, 5s rRNA, 7SL RNA and U6 snRNA and is overexpressed in many transformed cell lines and tumors in vivo, since cells must duplicate its protein components before division. Therefore, in order to maintain rapid growth, cells must produce a high level of Pol III transcribed RNA, which requires the presence of the TFIIIB and TFIIIC2 transcription factor complexes. The TFIIIC2 complex is composed of five subunits, TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, that are overexpressed in adenovirus transformed cells as well as in malignant cells in vivo, such as ovarian carcinomas. TFIIIC2 recruits RNA pol III and TFIIIB to promoter elements and may be a key component in the deregulation of malignant cells. The TFIIIB complex includes the TATA-binding protein (TBP), TFIIB-related factor 1 (BRF1) and TFIIIB, the expression of which are also upregulated in transformed cells. In many carcinomas, the tumor suppressors retinoblastoma (RB) and p53 are inactivated, which affects their ability to bind and inactivate the function of TFIIIB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
배송/결제/교환/반품 안내
배송 정보
기본 배송비 |
| 교환/반품 배송비 |
|
---|---|---|---|
착불 배송비 |
| ||
교환/반품 배송비 |
|
결제 및 환불 안내
결제 방법 |
|
---|---|
취소 |
|
반품 |
|
환급 |
|
교환 및 반품 접수
교환 및 반품 접수 기한 |
|
---|---|
교환 및 반품 접수가 가능한 경우 |
|
교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
교환 절차 |
|
---|---|
반품 절차 |
|