Thermo Fisher Scientific KLF15 Polyclonal Antibody
KLF15 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot에 적합하며, Mouse 시료에서 반응합니다. 합성 펩타이드 항원 기반으로 제조되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): Tested dilution 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of KLF15 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2691026 |
Product Specific Information
This target displays homology in the following species:
Cow: 92%, Dog: 93%, Guinea Pig: 93%, Horse: 91%, Human: 100%, Mouse: 93%, Rat: 100%
Target Information
KLF15 is a nuclear protein belonging to the Sp1 C2H2-type zinc-finger protein family with three C2H2-type zinc fingers. It acts as a transcriptional activator binding to the GA element of the CLCNKA promoter, regulating tissue-specific expression of CLCNKA and CLCNKB channel genes. KLF15 plays an essential role in adipogenesis through regulation of PPARG expression and functions as an inhibitor of cardiac hypertrophy. It also regulates mitochondrial acetyl-CoA synthase expression in skeletal muscle and may act as a transcriptional repressor of rhodopsin and IRBP promoters in the retina. Expression is high in liver, followed by heart, skeletal muscle, and kidney, but not in bone marrow or lymphoid tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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