Thermo Fisher Scientific CSF3 Monoclonal Antibody (OTI1G8), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:200

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

G-CSF (Granulocyte Colony Stimulating Factor) is a cytokine that stimulates production and antibacterial function of neutrophils and monocytes.
It is an 18.8 kDa protein with 175 amino acids and exists in multiple isoforms. G-CSF is produced by activated monocytes, macrophages, endothelial cells, fibroblasts, astrocytes, osteoblasts, and bone marrow cells.
It regulates proliferation, differentiation, and activation of hematopoietic cells and is expressed in various carcinoma and leukemia cells.
Clinically, G-CSF is used in treatments for infections, myocardial infarction, neutropenia, leukemia, and other immune disorders.
G-CSF dysfunction is associated with Kostmann Syndrome and serves as a marker for certain carcinomas.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.