Thermo Fisher Scientific FOLR4 Polyclonal Antibody

Applications

• Western Blot (WB): 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Peptide sequence: TCKSNWRGGW DWSQGKNRCP KGAQCLPFSH YFPTPADLCE KTWSNSFKAS
• Sequence homology:
  • Guinea Pig: 85%
  • Horse: 90%
  • Human: 100%

Target Information

FR4 is a heavily glycosylated 35 kD receptor for folic acid and the physiologic circulating form of the vitamin, N5-methyltetrahydrofolate. Natural Tregs have high levels of FR4 and, together with CD25, can be used to distinguish natural Tregs, effector T cells, memory-like T cells, and naive T cells. In vivo studies with eBioTH6 show a decrease in the number of CD4+CD25+ cells and an enhanced tumor response leading to the elimination of advanced stages of tumors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.